The Super-Peasants of Gluten, Syphilis
You are a common village peasant in the small town of Gluten:
Gluten is beside the Giblet River, which flows through Syphilis. (Names may sound familiar.)
You have heard rumors:
Emphysema has a power-hungry and greedy king, who has been taxing his people into poverty and hiring brutish tax collectors who take even more than the king demands.
Malaria has been terrorized by a ferocious monster.
Varicella is in the midst of a civil war.
You get little news from the isolated kingdom of Kwashiorkor, but all this matters little to you, for it is all a mere peasant can do to keep the weeds out of your garden. It seems like every day you pull them, and every day there are more than the day before.
Then one day...
BOOM! Cosmic radiation blast and everyone has superpowers!
Your superpower will be determined by your genetics. You will be able to make suggestions as to what you do or do not want, but I have 40 superpower options listed on a chart, and each one can only be received by someone of certain eye color, hair color, and blood type. Thus, a form of randomness.
This town has a parson, a blacksmith, a stablehand, a tailor (me?), a shopkeeper, a barber, a baker, a butcher, some farmers, and a passing stranger. All but the stranger know each other. All were hit by the blast. It may have killed some, but the survivors now have incredible powers and can choose to help someone in need of it...or just become a violent madman if they feel like it.