Well, the pain pill thing is related to the fighter career. Typically fighters end up taking a fair amount of pin pills, opium/morphine and the likes and usually they succumb to the addiction stage, as for running fast, not in the professional athlete style of running, more in the controlled running mix, about a half way level, can control breathing in running for a fairly long period of time but not for as long as most could do it, obviously. If that makes sense, trying to not make her overly good, but good enough to defend herself in some way, with hand to hand, since there is not really fighters of any kind in the group at the moment, this still makes her susceptible to gun play and all the other general stuff seeing as she'd need to get close and she has no stealth capabilities. 

*For physical weakness, I think hearing would be a good one to add in. Too many blows to the head in her career causing a hearing issue, making it easier to sneak up on her or not notice things as well as most could. Adding now.