I was thinking we could all be mercenaries hired by some mysterious figure to do all this stuff (quests and the like) with the independence of New Vegas in mind. That could open our characters up to a more broad range of moralities and affiliations. I mean, we could do the NV plotline if you want? But it might be hard to stay on so tight a track with so many people, going by how many have shown interest. I'm totally calling the ex-Followers of the Apocalypse character. Science! Yay!