Ok, so nukes were an example, you don't need them. Fuck it, go antimatter! Apparently, you have plenty of the stuff lying about, if you think you can fuel ships that fucking massive. Or better yet, just get a light vehicle mounted one and get some big fuck-off rockets on it. We already do that to kill planes, why not make them bigger, or in the future when we have better explosives just make them boom-ier, and shoot the dipshits as they descend with them!