What about using a Japanese city that hasn't been already featured in the anime? Like Osaka? Though a previously used city would be fun for making references. Even Kyoto would be fun, and was referenced before in 02 about being a location where the lines between the two worlds sometimes get blurred.

Or does it have to be Japanese at all? What about a group of European Digidestined?

-------Though it really doesn't matter to me. I'm just throwing out ideas. You know, making things more complicated for everybody. Haha. Whoops. ^^;