[quote=@Willy Vereb]
[@MetalLover]Since many people mentioned mutants, what kind of "fantastic" elements are allowed?
Even in Fallout the mutants are usually product of genetic experiments and the FEV virus.
Also didn't the nations used fusion nukes that are almost completely void of any fallout? Granted,  a destruction of this scale I bet there are plenty of other hazards.
Just saying.
[/quote]

"Mutants" with minor deformities are allowed. I do believe accounts of the children of survivors of Chernobyl and the Nuclear bombings of Japan resulted in some of them having deformities, so it would make sense that some of those would breed together during those two hundred years, areas with a larger populace, which needed more nukes, would most likely have more mutants.
So no, no Super Mutants like in fallout, but people with minor deformities can be used in story.
Now moving on to experiments, I was talking about how these bunkers (vaults) where used, maybe have on in your area that was used specifically for the experiments of creating a slave-like mutated human, if you bring up that as an example, as long as it isn't so far fetched, I'd be fine.