[quote=@thewizardguy]
[@Archmage MC]
Sure, but then he'd taste the poison and stop.

The heart virus was supposed to be an incredibly rare disease that was capable of killing Saiyans, who are immune to almost all diseases. And that laser thing is non-canon.
[/quote]

No its canon. Its in Dragon Ball Super, which the canonical continuation of Z. You could also just use nanotech or aerosol cyanide. Lots of underhanded ways to defeat things that can't regenerate tbh.

Or just be a smart krillin and use a kienzon to slice him in half after a solar flare. That works up to Semi perfect cell I think.