[quote=@Redrum]
To start, I was wondering if the Guardian's have any connection with the Spirits? Are they able to communicate, or converse via mind or dream? Or is it more along the lines of a typical summoning? Has Mordrem effected the oceans or sea life in the Dark Zone? Can Guardians have artificial implants? Be it for physical enhancements or due to a loss of a limb? If so, will that effect their connections to the Spirits within them or the magic they're capable of?
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Spirits that have escaped their natural embodiment inhabit their chosen sanctuaries, so they physically live inside Guardians' bodies. Guardians can interact with the physical apparitions, see them, and converse with them. However, spirits cannot verbalize, but they can show emotions through actions and movements.

Yes, sea life is affected. I haven't give any thought yet to how, but it's there. The most obvious sign would be receding shorelines. As Gaia exists in everything, it also exists in water. Therefore, Mordrem consume water as well.

Guardians gain all the physical enhancements they could ever want through spirit possession. But, if they lost a limb, then yes. Spirits are attracted to strength, the best of nature. Someone who is or becomes weak will not be able to protect them. So, an artificial limb could be interpreted as a weakness by spirits, which would lead the spirits to leave that Guardian.