Well, here's these, and I added some ideas to some of the relationships.

Rafe: Not only would these two get along over understanding the value of a buck, and over how hard they work to pay back Max's loan, but I can also see Spencer enjoying Rafe's easy-going nature because it [i]is[/i] easier to rope him into things. Spence wouldn't purposefully take advantage of it, not at all, but he would enjoy that he could get Rafe to hang out with him a lot because he likes his dry sense of humor and sarcasm. Also, they can be drinking buddies, because Spence likes a good drink after a hard day at the hospital. Maybe that's how they even met; they both frequent the local pub and Spence bought Rafe a drink because he's a [i]gentleman[/i] like that and they hit it off.

Avery: Because of Spencer's job, even with his loud personality, he knows how to flesh people out and so he would realize Avery is more quiet and he wouldn't be [i]as[/i] loud around her; he wouldn't want to scare her away. But, he'd still be talkative, and more than likely shove Pepper at her every chance he got. Maybe these two met because Avery had a panic attack out in public and she was rushed to the hospital, it was so bad? And Spence was her nurse and now he's a bit protective of her and goes out of his way to talk her ear off (by the way, she will be the second character, if you agree, to have met Spence through the hospital. We have an accident-prone group of people here, I'm glad Spencer can take care of y'all lol!).

Maximus: Hmm. I can see Spence hearing about Max through the grapevine, so to say, and coming to him in an unhappy fashion for a small loan for rent that month because he might have gotten carried away by accident. Spence would probably do most of the talking between them, honestly, and being a naturally curious person, ask about his lifestyle (whenever he found out, I don't know how it would get brought up). Not rudely and he would apologize if he thought he said something offensive, but he would probably ask questions, and that might be a bit annoying. He'd also want to read his books, because Spence likes to read in his free time, or whenever he's on his breaks at the hospital. Hey, Max could also rope Spencer into liking anime, because Spence is really open about entertainment options, and I'm sure Max would love to convert someone else into anime.

Alexei: With Alexei being so friendly and open, Spencer would for sure get along with him. I'm sure these two would have easy and friendly conversations that Spence would enjoy and Spence would probably talk about Alexei's accent being cool a lot, because Spence is easily entertained. I can see these two getting introduced by someone, though, I can't think of way they met otherwise.

Johanna: I can't think of anything else to add to their relationship because we fleshed it out pretty well already lol. Besides that yes, Spencer will definitely go with the whole 'soul mate' teasing and probably always be picking her up around the waist and squeezing her into the hugs just because he can.

Matt: Like we said, they met through a hospital visit. I say they bonded over a Captain America t-shirt because [i]win[/i]. I also like that they did go out; I can see Spence really liking Matt and I could see them quickly forming a tight relationship. Though, maybe Spencer doesn't push for another date because he doesn't wanna ruin the new, great friendship, and flirts openly with him (though, Spence is totally gonna be a big flirt anyway, how can he not be?) but also keeps his distance. I don't know, we'll see what happens in the rp with all that!

Anastasia: So, still on the fence about how they met, but I do wanna add, since Anastasia is so open and unreserved, this is probably someone Spencer will pick up in a hug and spin around for no reason, just because he can, and who he will talk excitedly at while always touching her hair and saying how much he loved it. I can just see that so clearly. I can also see him being [i]very[/i] supportive of her in her career and always telling her he would help in any way he can.

Luci: Once again, someone else Spence can be loud with! Since Luci is so energetic, and does so much, maybe these two met jogging one day? Because Spence jogs or runs each chance he gets. Maybe they both were leaving the apartment complex at the same time in workout clothes and Spence was like yo, let's run together!, and well, they became jogging/running buddies! 

Marcie: (we have the Joey of our group!) Spence doesn't get offended easily, at all, and so I can totally see him finding amusement in Marcie's personality, rather than being turned off by it. He would probably enjoy going out in public with her just to hear her talk and would get a kick out of it. Maybe they met through the butcher shop - Spencer wanted a big juicy steak for dinner one night and came in. Maybe he even thought Marcie was pretty and asked for her number. He called, they went out, and Marcie was, well, Marcie but Spencer found her funny instead and asked to be friends, and they've been friends ever since. I can see him being very supportive of her, too, and always teasing her about her brash nature, telling her to 'lighten up' or something.