[@Thundercrash]

Yes. It's not like Star Wars with loads of species interspersing and all that jazz. Most space-faring creatures stick to their own area and typically don't wander out of it, humans included. You can run into aliens but it's unlikely. There will be foreign alien life in this though.

[@Subject Zero]
In terms of robotics, there is full-on AI and there are a number of sentient robots which the Inquisitors seem to actually like due to their thoughts on robotics and technology.