[quote=@mdk] lol @ "statistical sampling." You can't just throw a science-ish word into your willful ignorance and turn it into evidence. [/quote] I can throw in any sciency words I like: Amplicons greater than 5 kb may require further optimization. The point is the vast majority of links I follow from conversations like this are hardly worth the effort as a result I no longer expend that effort. Clustered regularly interspaced short palindromic repeats.