[quote=@Lurking Krog]
So how are you handling the birth signs. I know in Skyrim there are some that are different than in Oblivion.

For example The Lord. In Oblivion it allows 90 hp heal but weak to fire whereas in Skyrim it grants damage reduction to both physical and magica attacks.
[/quote]

It's mostly for flavour rather than actual in-game effects. Something like the Lord would probably be portrayed as a robust person who takes well to healing potions/ magic while having an aversion to flame. That's entirely on the players to decide how much or little their birth signs effect them.