Fortunately, Ryou and Shira wouldn't have to actually worry about the bags. Not as the world started to spin and they became impossibly tired. So tired in fact, that they would feel an insurmountable weakness seep through their bodies slowly eating away at their strength. They'd become weak and exhausted in only a few minutes and the hard labor of moving the bags would feel impossibly tiring. Eventually, both of them would find that they would just feel a moment where their head would spin then...Complete darkness as they both would pass out. Likely, neither of them would realize that the food was laced with a narcotic and a paralytic sedative. That coupled with the fact that the two hadn't slept in a good while put them in all the worse of a situation. Likely, the intoxicating allure of sleep would easily engulf the two and drag them down into an euphoric abyss. If they had, they both could have probably made preparations to counterbalance it, but it was fast acting and not even the Houzi's special properties would save him the moment the toxic properties of the food were metabolized into his system. There was no way to resist the poison after it already settled. Not even if they were medical ninja, at least as a pair of Genin. The moment the symptoms started to set in it was too late. 

Likely, neither of the young Genin would have realized that the food had been a trap until, well, they were collapsing into a deep, dark slumber.