XD That would be very funny, I think Joe'd eventually get tired of her shit, grab her by the shoulders, shake her and shout. "I LIKE DICK! I AM GAY! YOU HEAR ME?! I WILL NEVER BE INTO YOU, I AM INCAPABLE OF FEELING ATTRACTION TOWARD YOUR GENDER, YOU CRAZY PSYCHO BITCH!"
And then she'd go from Yandere to Yangire and attempt to brutally murder him with whatever is on hand at the time.