Here comes the plot.
So there's a city called Hope, which floats in the sky. A superhero-wannabe called Captain Awesome with the power of lightning rises up, together with a few players who have long since disappeared. There's a climatic fight between Abbadon the Demon Lord and Captain Awesome during which several nuclear generators are destroyed, causing portals to an alternate version of Hope called Fear to open. In Fear there are dimensional opposites of each of the players, except those who had at this point already disappeared without any explanation. The heroes from Hope move to this new location, with the exception of Captain Awesome who dies in order to save Hope from falling into the abyss.
Fear is ruled by three crime lords, the Lords of Fear. Kami, Captain Awesome's opposite, rules an organization called God's Tears, a church which is a cover for a powerful group that controls the economy and trade of Fear, manipulating all events that occur within it's bounds. Aisyle, Ellysia's opposite, who leads Fault, a group of rogues and scoundrels that perform assassinations and sabotage missions. Lastly, there's Appolyon, who rules the Corrupted Quarter, an area filled with demons and hellspawn. He's quite obviously Abbadon's opposite. The heroes interact with these crime lords, before Kami takes control of Fault, forces Aisyle into slavery, and creates a pact with the demon lord Appolyon. This effectively makes her the sole Lord of Fear.
Kami, however, has much bigger plans. She sends the heroes, now mostly under her control, back to Hope to scout their defenses. However, an unstable portal takes a character that has left back in time to where she saves Captain Awesome. He then continues to become the city's sole protection against Kami, as Ellysia and Aisyle work to further Kami's goals at gun point (metaphorically speaking). Eventually Kami launches an all-out attack, slaughters Captain Awesome, and sends out her brainwashing spiders to take over all major political and religious figures. However, in the time it takes for her to make her first appearance on Hope, the heroes have a brief chance to kill her before she gains complete control over the world economy.