Prima - The leader of the Thirteen, a warrior of light who wielded the Star Saber.
Vector Prime - The master of time and space, which he could manipulate through his Blades of Time.
Alpha Trion - Holder of the Quill, which he uses to record the past, present, and future of Cybertron in the Covenant of Primus in his role as recordskeeper of the Primes.
Solus Prime - The master artificer and creator of many of the Primes' weapons through use of her incredible Forge. She was the first female Cybertronian.
Micronus Prime - The conscience of the Thirteen, and the first Mini-Con, able to link up with and enhance the power of his siblings through the use of his Chimera Stone.
Alchemist Prime - Student of the elemental structure of the natural world, aided in this by his Lenses, which allowed him to see further and deeper than anyone, in both material and spiritual senses. Co-founder of Cybertronian civilization with Alpha Trion.
Nexus Prime - The first and greatest combiner, granted the ability to divide himself into separate forms by his Enigma of Combination. Unpredictable, fascinated by change, and a lighthearted prankster.
Onyx Prime - The first beast-form Cybertronian, a primitive and spiritual being able to view other times, places, souls and even the afterlife through his three-faced Triptych Mask.
Amalgamous Prime - The joker of the Thirteen and the first Shifter, unpredictable and easygoing. He was first Cybertronian with the ability of transformation, granted him by his Transformation Cog, which became the basis for the cogs in all subsequent Trasnformer life.
Quintus Prime - A daydreamer and perfectionist whose drive to express his ideas led him to become a scientist. His artifact was the Emberstone, which gave him the ability to create life; the Quintessons were among his creations.
Liege Maximo - The manipulator. Though his artifact was notionally the toxin-loaded Legian Darts, his real skill was his ability to talk others into his way of thinking—a black art that ultimately caused the downfall of the Thirteen.
Megatronus - The warrior of darkness, Prima's opposite number, whose role as the necessary counterbalance set him apart from his fellow Primes. His artifact was the Requiem Blaster, created for him by Solus; this act began a doomed romance between the two that led to his turning on his brothers and becoming known as The Fallen.
Optimus Prime - The mediator of the Primes, who united the Thirteen by being the first among them to raise an arm in greeting. He would subsequently be reincarnated as Orion Pax.