Because us lefties know we have more important things to do with our dominate hand. So, use the other hand.
my mouse
A Fluttershy plush.
SHALL I GO FURTHER?
Well if I stretch my arm out a little there's a Virizion plush, which is marginally more culturally acceptable than a Fluttershy plush but essentially the same thing.
<Snipped quote by Antarctic Termite>
No, what's culturally unacceptable is the infamous "Lyra Plushie".