Hey, since we already did Gwen and Mary-Jane, can we do Lana and Lois?
....in what context?
EDIT: Assuming you mean in the "which do you like better" context, and not the "hey everyone I wrote a sex scene" context, it's Lois in a heartbeat. Lana Lang, much like an awful lot of Superman's supporting cast really, is an add-on, an optional character who can add extra context to Clark's life (especially in his early days), but isn't necessarily critical. On the other hand, as we saw with his unfortunate New 52 incarnation, Superman straight-up does not work without Lois Lane. Yes, when she's written poorly, her type-A personality goes from 'strong-willed and confident' to 'scary bitch,' but having someone who has a strong enough spirit to impress and bewilder even the Man of Steel is integral to Clark's connection to humanity.
It also helps that Lois has pretty much always been the same basic person since Day One-- the details change and the finer points of her personality differ, but since the word go Lois has always been a fearless spitfire reporter. Lana, on the other hand, is all over the place in her incarnations, sometimes just the earnest girl-next-door, sometimes a savvy business mogul, sometimes a famous supermodel, whatever the hell was going on with her in Smallville, etc. Every time she shows up, there's really no telling who she's going to be.
I have my own ideas of who Lana is going to be in this RP, but in the general sense, Lois wins in an easy walk.
Now, if we're talking about that
other context.....I mean, I'm not saying I'll do it, but I'm also not saying I won't.....